Our Mission
Puma Biotechnology is a biopharmaceutical company dedicated to the acquisition, development, and commercialization of novel therapeutics for the treatment of cancer.
Clinical Trials
ALISCA™: ALISertib in CAncer
Figuring Out Fatigue
Cancer-related fatigue is more than just feeling tired.1 It can feel like your “battery” is always running low. If you’ve felt this way, you’re not alone. Over 80% of people going through cancer treatment report having fatigue.1
What Does Cancer-Related Fatigue Feel Like?
Fatigue from cancer is often different than normal tiredness. It doesn’t always go away with sleep or rest.1 You might feel like:
- You can’t focus or remember things
- You’re too tired to do simple tasks
- You can’t enjoy things you used to1
Why Am I So Tired?
Fatigue can come from more than just treatment. Medications and side effects play a role, but so do:
- Worry about your health or the future
- Stress about work, family, or money
- Trying to keep things ‘normal’
- Not wanting to impose on others by asking for help
- Poor sleep or anxiety11
Think of Your Energy Like a Battery
Your energy is like a phone battery. Each task uses up energy. If you don’t recharge, it runs out. Recharging can mean different things: taking a nap, resting, talking to a friend, or simply doing less.
Tips to Manage Fatigue
While you may not get rid of fatigue completely, here are some ways to help manage it:
- Plan ahead – Do important tasks when you have more energy.
- Take naps – Don’t feel guilty for resting.
- Ask for help – Let others cook, clean, or run errands. At work, ask about working from home or flexible hours.
- Gentle exercise – Talk to your doctor about how often and what kind of exercise might help improve fatigue.
- Talk to your doctor – They may have helpful advice.1
What to Tell Your Healthcare Team
Saying “I’m tired” isn’t always enough. Give your healthcare team more information so they better understand what you’re going through:
- When are you most tired?
- How long does it last?
- What’s harder to do now?
- What factors such as sleep, exercise, food, and/or side effects might play a part in your fatigue?2
You Are Not Lazy
Feeling tired from cancer isn’t the same as being lazy. Fatigue is a real side effect.1 It can affect how you think, feel, and function.1
Be kind to yourself. You don’t have to do it all. Resting isn’t giving up. Asking for help doesn’t
make you weak.
Final Thoughts
With the right tools and support, you can conserve your energy, speak up for your needs, and take care of yourself in new ways.
-
1
National Cancer Institute, “Cancer Fatigue,” Updated: September 20, 2024, https://www.cancer.gov/about-cancer/treatment/side-effects/fatigue Accessed November 3, 2025.
-
2
National Cancer Institute, “Fatigue (PDQ®)–Health Professional Version,” Updated: November 6, 2024, https://www.cancer.gov/about-cancer/treatment/side-effects/fatigue/fatigue-hp-pdq Accessed November 3, 2025. 2025.
MRC-US-ALI-00125 11/25